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Three Brazilian sisters, oldest living trio, share secrets to longevity at 316 years combined

Three Brazilian sisters, celebrated by Guinness World Records for their remarkable combined age of 316 years, are now the subject of a new study spearheaded by scientist Mayana Zatz from University of São Paulo. Researchers are looking to identify genetic traits associated with longevity, which could provide valuable insights into sustaining physical and cognitive health as people age.

BRIC Team
BRIC Team
Jun 24, 2026 · 1 min read · 3 views
Three Brazilian sisters, oldest living trio, share secrets to longevity at 316 years combined

Key Takeaways

  • The three sisters, aged 316 years combined, were recognized by Guinness World Records for their exceptional longevity.
  • Scientist Mayana Zatz leads the DNA Longevo Project at the University of São Paulo to study the sisters' genetic traits.
  • Zatz stated, 'Through DNA testing, we look for protective genes, and we know there are several of them.'
  • The research aims to compare centenarians and nonagenarians to identify traits linked to longevity.
  • Involving more families with multiple centenarians will enhance the precision of the study's findings, according to Zatz.

Three Brazilian sisters,now recognized by Guinness World Records as oldest living trio of siblings,might unlock secrets of longevity . At combined age of 316 years,their case draws researchers eager to probe aging's biological roots .

The DNA Longevo Project,led by scientist Mayana Zatz from University of São Paulo,seeks to uncover factors behind long life. Zatz,heading the university's Human Genome Research Centre,stressed importance of studying such individuals to find genetic traits linked to longevity. “Through DNA testing,we look for protective genes,and we know there are several of them,” she said.

Researchers compare centenarians and nonagenarians with those facing frailty or cognitive decline. Aim to spot traits tied to long,healthy life. The sisters’ longevity might shed light on why some keep physical,cognitive strength into old age .

Zatz said more families with multiple centenarians involved mean more accurate findings. Study continues to explore genetic,lifestyle mix leading to longer,healthier life. But can science truly decode the mystery…?

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